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The use as the only treatment of short-acting bronchodilators, such as ventolin (salbutamol), either continuously or on demand, may increase the risk of severe asthmatic attacks, according to pulmonologists from the Hospital del Mar Pneumology Service. Evidence that certifies a study led by doctors from this service and from the center's Pharmacy, and by researchers from the Hospital del Mar Medical Research Institute (IMIM), which publishes the journal Archives of Bronconeumology. The signatories of the work point out that the alternative with the best results is the treatment with the association of inhaled corticosteroids and formoterol, both drugs already existing and available for the treatment of asthma.

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Specialists believe that the treatment currently used in most cases, based solely on short-acting bronchodilators, known as ventolin, may increase the risk of severe asthmatic attacks. In the cases of patients with mild asthma, "treatment with the association of inhaled corticosteroids and formoterol on demand may have a beneficial impact on them, especially if we take into account the problem of poor compliance with inhaled treatment in these types of patients, since this alternative would help to maintain a high effectiveness on severe exacerbations ", explains Dr. Pilar Ausín, pulmonologist at Hospital del Mar and main author of the study.

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Mild asthma is the most frequent, but a significant percentage of patients undergo inadequate control, only with ventolin on demand. This causes a temporary relief of symptoms, but at the same time, perpetuates or increases bronchial inflammation, increasing the risk of a serious crisis, which can lead to hospitalization and even death. "Treatment only with this drug on demand has to be re-evaluated, even in the first stages of treatment," says the head of the Pulmonology Service, Dr. Joaquim Gea. Furthermore, its substitution by inhaled corticosteroids is recommended by the international guideline on asthma Global Initiative for Asthma (GINA). In fact, the Spanish Guide for the Management of Asthma (GEMA), has gone from advising treatment only with salbutamol for mild patients to incorporating treatment with inhaled corticosteroids in its latest review, carried out last May, although it maintains short-acting bronchodilators with a maximum of two puffs per month (previously two per week).

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